HIV Vaccine Fails. What’s Next?

NIH on HIV Vaccine Failure: ‘Get YourHIV-Negative, At-Risk Patients on PrEP Tomorrow’ – Medscape – Sep 02, 2021.


Last year, Katherine Gill, MBChB, an HIV prevention researcher in Cape Town, South Africa, realized how jaded she’d become to vaccine research when the Pfizer COVID-19 vaccine came back as 95% effective. In her career conducting HIV clinical trials, she’d never seen anything like it. Even HIV prevention methods she had studied that had worked, like the dapivirine ring, only had an overall efficacy of 30%.

The COVID-19 success story started to soften her views toward another vaccine trial she was helping to conduct, a vaccine trial in HIV that used the same platform as Johnson & Johnson’s successful COVID-19 vaccine.

“When the COVID vaccine was cracked so quickly and seemingly quite easily, I did start to think, ‘Well, maybe…maybe this will work for HIV,’ ” she told Medscape Medical News.

That turned out to be false hope. This week, the National Institutes of Health (NIH) announced that the trial Gill was helping to conduct, HVTN 705, was stopping early because it hadn’t generated enough of an immune response in participants to justify continuing. It was the second HIV vaccine to fail in the last year. It’s also the latest in what has been a litany of disappointments in the attempt to boost the human immune system to fight HIV without the need for ongoing HIV treatment.

Read full story on Medscape.

WORLD AIDS DAY POEM

I’m stranded! From an infected womb i was birthed, i’m stranded!

they called me “h. Ivy” and this name went viral, they teased, i wept…..

 i kept on shifting aside and aside waiting for someone to sit by my side but the space became wide and wide ,with sadness i slept…..

 my friends drove me insane,they all trampled on me,i crept…..

This HIV/AIDS was encrypted in my genes, i’m stranded!

 I’m scarred! By an infected blade i was cut, i’m scarred!

It was just a scratch, a minor touch, a mere cut but the wound was deep, i sunk…..

 i became an alcoholic that never missed her tot, i was always drunk…..

They said i had a stench and they called me a wench, i sat lonely on every bench…..

This HIV/AIDS hooked me up, i’m scarred!

 I’m tainted! With an infected blood i was transfused, i’m tainted!

 They said i was polluted, adulterated and infused with a deadly disease…..

They hash tagged me with harsh tags that pulled me down, i was unfollowed…..

 i wanted to be seen, to be heard and to be felt but i was never wanted, they behaved like racists…..

 This HIV/AIDS  painted me black, I’m tainted!

I’m broken! I laid on a bed of roses with an infected lover, i’m broken!

 i tasted the sweetness of his lips, the bite was a happy delight, i was wasted…..

Inches deep, i never imagined these deep presses would leave me depressed and get me infected…..

I was loud on heat above cloud nine and i kept the memories like files on an icloud, i never thought i was going six feet under the cold pit…..

 This HIV/AIDS turned my pleasure to pain, i’m broken!

 I’m provoked! This is all blinding and i’ve already lost sight, I’m provoked!

The pages of my death note are before me and my indelible ink is set to imprint a final goodbye, I’m ready to die…..

I’m caught in between the lines of my pages and it is hard to tell my tale to the children of a future i might never get to see…..

This is me, I’m making signatures of how they made me feel and i’m going to carve the thoughts of my mind into the sculptures of tomorrow …..

Something drops heavily on the bare naked floor, lights out, i’m i dead or alive, intermission!, I’m still provoked!

A new day comes with a new celebration and a new awareness…..

We drop the sharp knives and the deadly pills and we stay positive even when we test positive…..

Our banners are raised to the skies with messages of hope to victims and a word to the wise…..

For when tomorrow comes, every one needs to know about HIV/AIDS but no one has to get HIV/AIDS…..

A new day comes yet again, we thrived.

Mherchylhynn

I’m Mercy Oduro Anti
A recent Bpharm graduate from Central University
I’m a former Laspag vice president and also a former member of the editorial board
I love to write, research and watch series
I believe in determination, perseverance and hardwork